When there are multiple changes made in a Visual Edit variation, it creates dependencies within the campaign. The changes are applied chronologically, so-to-speak, so in the event that one of the changes cannot be made, your recent edits will not reflect.
Changes that might affect your visual edit campaign may include layout changes, renaming of selectors in the native code, etc.
Generally, creating a lot of changes to the same variation of a visual edit campaign is not recommended so if you notice changes are not being stored to a variation with multiple changes it is advised to create a new campaign.
If the changes in a new visual edit campaign are still not reflecting, it's likely time to open a support ticket.
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